The episode you're referring to is Season 4, Episode 7 of Young Sheldon. The episode originally aired on November 18, 2020.
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Sheldon’s first day of college is derailed by his new philosophy professor, Dr. Dora Ericson . Her teachings on skepticism and the idea that "nothing can be proven for certain" deeply upset Sheldon, who views science as absolute truth. He attempts to drop the class but ends up in further debates about reality and existence. The episode you're referring to is Season 4,
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