The heartbeat of the series is the relationship between Michael Scofield (Wentworth Miller) and Lincoln Burrows (Dominic Purcell). When Lincoln is framed for a crime he didn’t commit and sent to death row at Fox River State Penitentiary, Michael—a brilliant structural engineer—executes an unthinkable plan. He tattoos the prison’s blueprints onto his body, commits a bank robbery to get incarcerated alongside his brother, and begins the most complex breakout in history. Season by Season: The Evolution of a Thriller