, TX: Served as the primary filming hub for Season 2 and Season 3. Local towns like Little Elm

(Season 3): While set in Panama, the exterior and yard scenes were largely filmed at the Historic Swift & Co. Plant

The most iconic location of the series is Fox River—the maximum-security prison that serves as the primary setting for Season 1.

After the brothers are recaptured and "killed," Season 4 sees them working for the Company in Los Angeles.